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Zhejiang Fangge Pharmaceutical Co., Ltd Zhejiang Fangge Pharmaceutical Co., Ltd

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Содержание полисахаридов: 35%
Применяется для профилактики и лечения онкологических заболеваний: простаты, предстательной железы, легких, молочной железы, шейки матки, тела матки, печени, почки, мочевого пузыря, бронха, меланоме, лимфоме, глиобластоме и астроцитоме, миеломной болезни, саркоме, лейкозе

Растворимый в воде экстракт (порошок) из клеток Рейши или Линчжи (Ganoderma). 
Упаковка из 15 металлизированных пакетиков.
По 2 грамма экстракта в пакетике.
Общий вес препарата – 30 грамм. 

Подробнее

27 Осталось

В наличии

2 400 руб

Печать

При покупке этого экстракта Bы получите 60 рублей скидки на следующий заказ.

Рейши.
Ganoderma lucidum. 
Гриб ганодерма. Линчжи.

Состав: 100% тело Ganoderma lucidum
Содержание полисахаридов: 35%.

 

Свидетельство о государственной регистрации: № RU.77.99.88.003.Е.003317.02.15 от 11.02.2015 г. Бланк №0262512  Смотреть на сайте Госрестра
Является заменителем препарата Lentinan (Лентинан).

Химический состав действующих веществ:

полисахариды: бета-D-глюкан (G-1);
ганодераны А,В,С;
GL-1(арабиноксилоглюкан);
FA, FI, FI-1, D-6;
тритерпеноиды: ганодеровые кислоты A,B,C,D,R,S,G,F,H,K,Y;
ганодермическая кислота;
стероид ganodosterone;
ненасыщенная жирная олеиновая кислота;
полипептид Ling Zhi -8 (LZ-8).

Фармакодинамика:

Противоопухолевое воздействие через усиление механизма противоопухолевой резистентности организма:
направленная активация различных иммунных исполнительных элементов (возрастание NK-клеточной активности, усиление формирования цитотоксических Т-лимфоцитов (ЦТЛ), активизация макрофагов);
увеличение их жизненного цикла;
угнетение тритерпенами роста опухоли;
потенцирование различных лимфокинов (интерлейкина 1, 2 и 6);
увеличение синтеза альфа-ФНО (фактора некроза опухолей);
увеличение производства интерферона-альфа, и улучшение действия интерферона-гамма в 2-4 раза;
увеличение выработки перфоринов;
восстановление сниженной иммунологической реактивности, которая наблюдается при облучении или химиотерапии;
противодействие депрессивному воздействию цитостатиков на количество белых и красных кровяных клеток;
при химиотерапии и облучении облегчение таких симптомов, как: слабость, анорексия, рвота, сухость во рту, спонтанное потение и боль;
иммуномодуляция;
болеутоляющее действие;
противовоспалительные свойства;
гепатопротективный эффект, улучшение функционального состояния печени, уменьшение энзимопатии.

Основное действие:
Подавляет рост опухоли, останавливает распространения метастаз, включает процесс разрушения и уничтожения раковых клеток и метастаз, поднимает уровень иммунитета, сильно поддерживает организм в период химио- и лучевой терапии, снижает до минимума негативные последствия химио- и лучевой терапии, улучшает показатели анализов крови, притупляет болезненные ощущения, сильно увеличивает срок жизни. 

Читать подробно: ДЕЙСТВИЕ НА ОПУХОЛЬ >>

Суточная дозировка:
Профилактическая: 2 раза в день по 1 пакетику за 60 минут до или после еды.
Лечебная: 2-3 раза в день по одному пакетику за 60 минут до еды или после еды с обязательным сочетанием с другим препаратом.
Для достижения наилучших результатов рекомендуется принимать согласно правилам методики "ПРОГМА". Необходима наша консультация .
Не рекомендуется принимать более двух месяцев подряд.
Необходимо заменить на другой подходящий.

Описание:
Мелкодисперсный порошок, полностью растворимый в воде. Цвет может меняться от светлокоричневого до тёмно-коричневого.

Способ применения:
Высыпать содержимое пакетика в стакан со 100 мл горячей ~ 80°С воды, размешать до полного растворения порошка, охладить до приемлемой температуры. Выпить.

Побочные действия:
При повышенной чувствительности, в редких случаях, возможно появление лёгкой диспепсии. Редко наблюдались аллергические реакции, в виде крапивницы, на компоненты экстракта. На начальных стадиях приема возможно газообразование. Возможно понижение давления.

Противопоказания:
Только индивидуальная непереносимость.
Беременность, лактация - не проводились клинические испытания в этих группах.
Не желательно применять экстракт детям до 8 лет.

Взаимодействие с другими лекарственными средствами и продуктами:
Хорошо сочетается с цитостатиками. Также при терапии даёт более выраженный эффект в сочетании с экстрактами из других грибов. В этом случае дозы приёма экстракта должны быть скорректированы специалистом.

Условия хранения:
Хранить при комнатной температуре (5-25 °С) в оригинальной упаковке.

Производитель: 
Zhejiang Fangge Pharmaceutical Co., Ltd
QINGYUAN, CHINESE MUSHROOM CITY, No. 1 
ECOLOGICAL ENVIRONMENT TOWN OF CHINA,
ZHEJIANG PROVINCE
CHINA
Стандарт производства и качества: GMP (Good Manufacturing Practice)

Methanolic Extract of Ganoderma lucidum Induces Autophagy of AGS Human Gastric Tumor Cells.

Reis FS, Lima RT, Morales P, Ferreira IC, Vasconcelos MH.

Molecules. 2015 Sep 29;20(10):17872-82. doi: 10.3390/molecules201017872.

Immunomodulatory Protein from Ganoderma microsporum Induces Pro-Death Autophagy through Akt-mTOR-p70S6K Pathway Inhibition in Multidrug Resistant Lung Cancer Cells.

Chiu LY, Hu ME, Yang TY, Hsin IL, Ko JL, Tsai KJ, Sheu GT.

PLoS One. 2015 May 6;10(5):e0125774. doi: 10.1371/journal.pone.0125774. eCollection 2015.

Ganoderma lucidum polysaccharide extract inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation and function by inducing microRNA-125b.

Li A, Shuai X, Jia Z, Li H, Liang X, Su D, Guo W.

J Transl Med. 2015 Mar 26;13:100. doi: 10.1186/s12967-015-0465-5.

Tissue invasion and metastasis: Molecular, biological and clinical perspectives.

Jiang WG, Sanders AJ, Katoh M, Ungefroren H, Gieseler F, Prince M, Thompson SK, Zollo M, Spano D, Dhawan P, Sliva D, Subbarayan PR, Sarkar M, Honoki K, Fujii H, Georgakilas AG, Amedei A, Niccolai E, Amin A, Ashraf SS, Ye L, Helferich WG, Yang X, Boosani CS, Guha G, Ciriolo MR, Aquilano K, Chen S, Azmi AS, Keith WN, Bilsland A, Bhakta D, Halicka D, Nowsheen S, Pantano F, Santini D.

Semin Cancer Biol. 2015 Dec;35 Suppl:S244-75. doi: 10.1016/j.semcancer.2015.03.008. Epub 2015 Apr 10. Review.

Ganoderma Lucidum Pharmacopuncture for Teating Ethanol-induced Chronic Gastric Ulcers in Rats.

Park JH, Jang KJ, Kim CH, Kim JH, Kim YK, Yoon HM.

J Pharmacopuncture. 2015 Mar;18(1):72-8. doi: 10.3831/KPI.2015.18.008.

Exceedingly biocompatible and thin-layered reduced graphene oxide nanosheets using an eco-friendly mushroom extract strategy.

Muthoosamy K, Bai RG, Abubakar IB, Sudheer SM, Lim HN, Loh HS, Huang NM, Chia CH, Manickam S.

Int J Nanomedicine. 2015 Feb 20;10:1505-19. doi: 10.2147/IJN.S75213. eCollection 2015.

Ganoderma lucidum inhibits proliferation of human ovarian cancer cells by suppressing VEGF expression and up-regulating the expression of connexin 43.

Dai S, Liu J, Sun X, Wang N.

BMC Complement Altern Med. 2014 Nov 5;14:434. doi: 10.1186/1472-6882-14-434.

A comprehensive review of the structure elucidation and biological activity of triterpenoids from Ganoderma spp.

Xia Q, Zhang H, Sun X, Zhao H, Wu L, Zhu D, Yang G, Shao Y, Zhang X, Mao X, Zhang L, She G.

Molecules. 2014 Oct 30;19(11):17478-535. doi: 10.3390/molecules191117478. Review.

Fungal beta glucan protects radiation induced DNA damage in human lymphocytes.

Pillai TG, Maurya DK, Salvi VP, Janardhanan KK, Nair CK.

Ann Transl Med. 2014 Feb;2(2):13. doi: 10.3978/j.issn.2305-5839.2014.02.02.

CARI III inhibits tumor growth in a melanoma-bearing mouse model through induction of G0/G1 cell cycle arrest.

Park HJ.

Molecules. 2014 Sep 12;19(9):14383-95. doi: 10.3390/molecules190914383.

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential.

Wong KL, Wong RN, Zhang L, Liu WK, Ng TB, Shaw PC, Kwok PC, Lai YM, Zhang ZJ, Zhang Y, Tong Y, Cheung HP, Lu J, Sze SC.

Chin Med. 2014 Jul 19;9:19. doi: 10.1186/1749-8546-9-19. eCollection 2014. Review.

Khz-cp (crude polysaccharide extract obtained from the fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating P38 and NADPH oxidase-dependent generation of reactive oxygen species in SNU-1 cells.

Kim TH, Kim JS, Kim ZH, Huang RB, Chae YL, Wang RS.

BMC Complement Altern Med. 2014 Jul 10;14:236. doi: 10.1186/1472-6882-14-236.

A green chemistry approach for synthesizing biocompatible gold nanoparticles.

Gurunathan S, Han J, Park JH, Kim JH.

Nanoscale Res Lett. 2014 May 21;9(1):248. doi: 10.1186/1556-276X-9-248. eCollection 2014.

Ganoderma lucidum polysaccharides target a Fas/caspase dependent pathway to induce apoptosis in human colon cancer cells.

Liang Z, Guo YT, Yi YJ, Wang RC, Hu QL, Xiong XY.

Asian Pac J Cancer Prev. 2014;15(9):3981-6.

Clinical characteristics of gynecologic cancer patients who respond to salvage treatment with Lingzhi.

Suprasert P, Apichartpiyakul C, Sakonwasun C, Nitisuwanraksa P, Phuackchantuck R.

Asian Pac J Cancer Prev. 2014;15(10):4193-6.

Chemical characterization and antitumor activities of polysaccharide extracted from Ganodermalucidum.

Liang Z, Yi Y, Guo Y, Wang R, Hu Q, Xiong X.

Int J Mol Sci. 2014 May 22;15(5):9103-16. doi: 10.3390/ijms15059103.

An in vitro evaluation of graphene oxide reduced by Ganoderma spp. in human breast cancer cells (MDA-MB-231).

Gurunathan S, Han J, Park JH, Kim JH.

Int J Nanomedicine. 2014 Apr 8;9:1783-97. doi: 10.2147/IJN.S57735. eCollection 2014.

The multifaceted effects of polysaccharides isolated from Dendrobium huoshanense on immune functions with the induction of interleukin-1 receptor antagonist (IL-1ra) in monocytes.

Lin J, Chang YJ, Yang WB, Yu AL, Wong CH.

PLoS One. 2014 Apr 4;9(4):e94040. doi: 10.1371/journal.pone.0094040. eCollection 2014.

In vivo and in vitro anti-tumor effects of fungal extracts.

Wu HT, Lu FH, Su YC, Ou HY, Hung HC, Wu JS, Yang YC, Chang CJ.

Molecules. 2014 Feb 21;19(2):2546-56. doi: 10.3390/molecules19022546.

Triterpene-loaded microemulsion using Coix lacryma-jobi seed extract as oil phase for enhanced antitumor efficacy: preparation and in vivo evaluation.

Qu D, He J, Liu C, Zhou J, Chen Y.

Int J Nanomedicine. 2014;9:109-19. doi: 10.2147/IJN.S54796. Epub 2013 Dec 19.

Green synthesis of silver nanoparticles using Ganoderma neo-japonicum Imazeki: a potential cytotoxic agent against breast cancer cells.

Gurunathan S, Raman J, Abd Malek SN, John PA, Vikineswary S.

Int J Nanomedicine. 2013;8:4399-413. doi: 10.2147/IJN.S51881. Epub 2013 Nov 15.

Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathway.

Wu GS, Song YL, Yin ZQ, Guo JJ, Wang SP, Zhao WW, Chen XP, Zhang QW, Lu JJ, Wang YT.

PLoS One. 2013 Oct 29;8(10):e76620. doi: 10.1371/journal.pone.0076620. eCollection 2013.

Anti-lung cancer activity through enhancement of immunomodulation and induction of cell apoptosis of total triterpenes extracted from Ganoderma luncidum (Leyss. ex Fr.) Karst.

Feng L, Yuan L, Du M, Chen Y, Zhang MH, Gu JF, He JJ, Wang Y, Cao W.

Molecules. 2013 Aug 19;18(8):9966-81. doi: 10.3390/molecules18089966.

Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes.

Liao SF, Liang CH, Ho MY, Hsu TL, Tsai TI, Hsieh YS, Tsai CM, Li ST, Cheng YY, Tsao SM, Lin TY, Lin ZY, Yang WB, Ren CT, Lin KI, Khoo KH, Lin CH, Hsu HY, Wu CY, Wong CH.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13809-14. doi: 10.1073/pnas.1312457110. Epub 2013 Aug 1.

Anticancer activity of Amauroderma rude.

Jiao C, Xie YZ, Yang X, Li H, Li XM, Pan HH, Cai MH, Zhong HM, Yang BB.

PLoS One. 2013 Jun 20;8(6):e66504. doi: 10.1371/journal.pone.0066504. Print 2013.

Modulatory effect of Ganoderma lucidum on expression of xenobiotic enzymes, oxidant-antioxidant and hormonal status in 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in rats.

Deepalakshmi K, Mirunalini S.

Pharmacogn Mag. 2013 Apr;9(34):167-75. doi: 10.4103/0973-1296.111286.

Ganoderma tsugae Extract Inhibits Growth of HER2-Overexpressing Cancer Cells via Modulation of HER2/PI3K/Akt Signaling Pathway.

Kuo HP, Hsu SC, Ou CC, Li JW, Tseng HH, Chuang TC, Liu JY, Chen SJ, Su MH, Cheng YC, Chou WY, Kao MC.

Evid Based Complement Alternat Med. 2013;2013:219472. doi: 10.1155/2013/219472. Epub 2013 Apr 7.

Traditional Chinese medicine syndrome-related herbal prescriptions in treatment of malignant tumors.

Liu Z, Chen S, Cai J, Zhang E, Lan L, Zheng J, Liao L, Yang X, Zhou C, Du J.

J Tradit Chin Med. 2013 Feb;33(1):19-26.

<i>Ganoderma lucidum</i> polysaccharides counteract inhibition on CD71 and FasL expression by culture supernatant of B16F10 cells upon lymphocyte activation.

Sun LX, Lin ZB, Duan XS, Lu J, Ge ZH, Li M, Xing EH, Lan TF, Jiang MM, Yang N, Li WD.

Exp Ther Med. 2013 Apr;5(4):1117-1122. Epub 2013 Jan 29.

Anti-tumor effects of Ganoderma lucidum (reishi) in inflammatory breast cancer in in vivo and in vitro models.

Suarez-Arroyo IJ, Rosario-Acevedo R, Aguilar-Perez A, Clemente PL, Cubano LA, Serrano J, Schneider RJ, Martínez-Montemayor MM.

PLoS One. 2013;8(2):e57431. doi: 10.1371/journal.pone.0057431. Epub 2013 Feb 28.

Apoptotic and Immune Restoration Effects of Ganoderic Acids Define a New Prospective for Complementary Treatment of Cancer.

Radwan FF, Perez JM, Haque A.

J Clin Cell Immunol. 2011 Dec 11;S3:4.

Mushroom Ganoderma lucidum prevents colitis-associated carcinogenesis in mice.

Sliva D, Loganathan J, Jiang J, Jedinak A, Lamb JG, Terry C, Baldridge LA, Adamec J, Sandusky GE, Dudhgaonkar S.

PLoS One. 2012;7(10):e47873. doi: 10.1371/journal.pone.0047873. Epub 2012 Oct 30.

Khz (fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating JNK and NADPH oxidase-dependent generation of reactive oxygen species.

Kim TH, Kim Js, Kim Zh, Huang RB, Wang RS.

PLoS One. 2012;7(10):e46208. doi: 10.1371/journal.pone.0046208. Epub 2012 Oct 8.

Synergistic Cytotoxic Effects of Ganoderma lucidum and Bacillus Calmette Guérin on Premalignant Urothelial HUC-PC Cells and Its Regulation on Proinflammatory Cytokine Secretion.

Yuen JW, Gohel MD, Ng CF.

Evid Based Complement Alternat Med. 2012;2012:147896. doi: 10.1155/2012/147896. Epub 2012 Aug 28.

Ergosterol peroxide isolated from Ganoderma lucidum abolishes microRNA miR-378-mediated tumor cells on chemoresistance.

Wu QP, Xie YZ, Deng Z, Li XM, Yang W, Jiao CW, Fang L, Li SZ, Pan HH, Yee AJ, Lee DY, Li C, Zhang Z, Guo J, Yang BB.

PLoS One. 2012;7(8):e44579. doi: 10.1371/journal.pone.0044579. Epub 2012 Aug 30.

Extracellular polysaccharides produced by Ganoderma formosanum stimulate macrophage activation via multiple pattern-recognition receptors.

Wang CL, Lu CY, Pi CC, Zhuang YJ, Chu CL, Liu WH, Chen CJ.

BMC Complement Altern Med. 2012 Aug 10;12:119. doi: 10.1186/1472-6882-12-119.

Enhanced production of ganoderic acids and cytotoxicity of Ganoderma lucidum using solid-medium culture.

You BJ, Lee HZ, Chung KR, Lee MH, Huang MJ, Tien N, Chan CW, Kuo YH.

Biosci Biotechnol Biochem. 2012;76(8):1529-34. Epub 2012 Aug 7.

BreastDefend™ prevents breast-to-lung cancer metastases in an orthotopic animal model of triple-negative human breast cancer.

Jiang J, Thyagarajan-Sahu A, Loganathan J, Eliaz I, Terry C, Sandusky GE, Sliva D.

Oncol Rep. 2012 Oct;28(4):1139-45. doi: 10.3892/or.2012.1936. Epub 2012 Jul 26.

Ganoderma tsugae Induces S Phase Arrest and Apoptosis in Doxorubicin-Resistant Lung Adenocarcinoma H23/0.3 Cells via Modulation of the PI3K/Akt Signaling Pathway.

Yu YH, Kuo HP, Hsieh HH, Li JW, Hsu WH, Chen SJ, Su MH, Liu SH, Cheng YC, Chen CY, Kao MC.

Evid Based Complement Alternat Med. 2012;2012:371286. doi: 10.1155/2012/371286. Epub 2012 Jun 26.

Ginseng and Ganoderma lucidum use after breast cancer diagnosis and quality of life: a report from the Shanghai Breast Cancer Survival Study.

Bao PP, Lu W, Cui Y, Zheng Y, Gu K, Chen Z, Zheng W, Shu XO.

PLoS One. 2012;7(6):e39343. doi: 10.1371/journal.pone.0039343. Epub 2012 Jun 20.

Inhibition of lysosome degradation on autophagosome formation and responses to GMI, an immunomodulatory protein from Ganoderma microsporum.

Hsin IL, Sheu GT, Jan MS, Sun HL, Wu TC, Chiu LY, Lue KH, Ko JL.

Br J Pharmacol. 2012 Nov;167(6):1287-300. doi: 10.1111/j.1476-5381.2012.02073.x.

Recent developments in mushrooms as anti-cancer therapeutics: a review.

Patel S, Goyal A.

3 Biotech. 2012 Mar;2(1):1-15. Epub 2011 Nov 25.

Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial.

Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X.

Evid Based Complement Alternat Med. 2012;2012:809614. doi: 10.1155/2012/809614. Epub 2011 Dec 10.

Anti-invasive activity of ethanol extracts of Ganoderma lucidum through tightening of tight junctions and inhibition of matrix metalloproteinase activities in human gastric carcinoma cells.

Jang KJ, Son IS, Shin DY, Yoon HM, Choi YH.

J Acupunct Meridian Stud. 2011 Dec;4(4):225-35. doi: 10.1016/j.jams.2011.09.013. Epub 2011 Oct 20.

Recombinant Lz-8 from Ganoderma lucidum induces endoplasmic reticulum stress-mediated autophagic cell death in SGC-7901 human gastric cancer cells.

Liang C, Li H, Zhou H, Zhang S, Liu Z, Zhou Q, Sun F.

Oncol Rep. 2012 Apr;27(4):1079-89. doi: 10.3892/or.2011.1593. Epub 2011 Dec 14.

Ling Zhi-8 mediates p53-dependent growth arrest of lung cancer cells proliferation via the ribosomal protein S7-MDM2-p53 pathway.

Wu CT, Lin TY, Hsu HY, Sheu F, Ho CM, Chen EI.

Carcinogenesis. 2011 Dec;32(12):1890-6. doi: 10.1093/carcin/bgr221. Epub 2011 Oct 7.

ReishiMax, mushroom based dietary supplement, inhibits adipocyte differentiation, stimulates glucose uptake and activates AMPK.

Thyagarajan-Sahu A, Lane B, Sliva D.

BMC Complement Altern Med. 2011 Sep 19;11:74. doi: 10.1186/1472-6882-11-74.

Ganoderma lucidum (Reishi) inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer.

Martínez-Montemayor MM, Acevedo RR, Otero-Franqui E, Cubano LA, Dharmawardhane SF.

Nutr Cancer. 2011;63(7):1085-94. doi: 10.1080/01635581.2011.601845. Epub 2011 Sep 2.

Study of the extraction process and in vivo inhibitory effect of ganoderma triterpenes in oral mucosa cancer.

Gao Y, Zhang R, Zhang J, Gao S, Gao W, Zhang H, Wang H, Han B.

Molecules. 2011 Jun 24;16(7):5315-32. doi: 10.3390/molecules16075315.

"And what other medications are you taking?".

Gordan JD, Chay WY, Kelley RK, Ko AH, Choo SP, Venook AP.

J Clin Oncol. 2011 Apr 10;29(11):e288-91. doi: 10.1200/JCO.2010.32.8054. Epub 2011 Jan 18. No abstract available. 

Herbal therapy use by cancer patients: a literature review on case reports.

Olaku O, White JD.

Eur J Cancer. 2011 Mar;47(4):508-14. doi: 10.1016/j.ejca.2010.11.018. Epub 2010 Dec 23. Review.

Promoting effects of Ganoderma lucidum polysaccharides on B16F10 cells to activate lymphocytes.

Sun LX, Lin ZB, Li XJ, Li M, Lu J, Duan XS, Ge ZH, Song YX, Xing EH, Li WD.

Basic Clin Pharmacol Toxicol. 2011 Mar;108(3):149-54. doi: 10.1111/j.1742-7843.2010.00632.x. Epub 2010 Oct 22.

Induction of apoptosis by ethanol extracts of Ganoderma lucidum in human gastric carcinoma cells.

Jang KJ, Han MH, Lee BH, Kim BW, Kim CH, Yoon HM, Choi YH.

J Acupunct Meridian Stud. 2010 Mar;3(1):24-31. doi: 10.1016/S2005-2901(10)60004-0.

Medical mushrooms used for biochemical failure after radical treatment for prostate cancer: an open-label study.

Yoshimura K, Kamoto T, Ogawa O, Matsui S, Tsuchiya N, Tada H, Murata K, Yoshimura K, Habuchi T, Fukushima M.

Int J Urol. 2010 Jun;17(6):548-54. doi: 10.1111/j.1442-2042.2010.02528.x. Epub 2010 Apr 19.

Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.

Chen NH, Liu JW, Zhong JJ.

Pharmacol Rep. 2010 Jan-Feb;62(1):150-63.

Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis.

Ferretti R, Palumbo V, Di Savino A, Velasco S, Sbroggiò M, Sportoletti P, Micale L, Turco E, Silengo L, Palumbo G, Hirsch E, Teruya-Feldstein J, Bonaccorsi S, Pandolfi PP, Gatti M, Tarone G, Brancaccio M.

Dev Cell. 2010 Mar 16;18(3):486-95. doi: 10.1016/j.devcel.2009.12.020.

Ganoderic Acid DM: An Alternative Agent for the Treatment of Advanced Prostate Cancer.

Johnson BM, Doonan BP, Radwan FF, Haque A.

Open Prost Cancer J. 2010 Jan 1;3:78-85.

A water-soluble extract from cultured medium of Ganoderma lucidum (Reishi) mycelia attenuates the small intestinal injury induced by anti-cancer drugs.

Kashimoto N, Ishii S, Myojin Y, Ushijima M, Hayama M, Watanabe H.

Oncol Lett. 2010 Jan;1(1):63-68. Epub 2010 Jan 1.

Supplements for immune enhancement in hematologic malignancies.

Sze DM, Chan GC.

Hematology Am Soc Hematol Educ Program. 2009:313-9. doi: 10.1182/asheducation-2009.1.313. Review.

Ganoderma lucidum extracts inhibited leukemia WEHI-3 cells in BALB/c mice and promoted an immune response in vivo.

Chang YH, Yang JS, Yang JL, Wu CL, Chang SJ, Lu KW, Lin JJ, Hsia TC, Lin YT, Ho CC, Wood WG, Chung JG.

Biosci Biotechnol Biochem. 2009 Dec;73(12):2589-94. Epub 2009 Dec 7.

The effect of a novel botanical agent TBS-101 on invasive prostate cancer in animal models.

Evans S, Dizeyi N, Abrahamsson PA, Persson J.

Anticancer Res. 2009 Oct;29(10):3917-24.

Gandoderma lucidum extract promotes immune responses in normal BALB/c mice In vivo.

Chang YH, Yang JS, Yang JL, Wu CL, Chang SJ, Lu KW, Kuo CL, Hsia TC, Chung JG.

In Vivo. 2009 Sep-Oct;23(5):755-9.

Complementary therapies, herbs, and other OTC agents: Reishi mushroom.

Cassileth B.

Oncology (Williston Park). 2009 Jul;23(8):728. No abstract available. 

Ganoderma lucidum Polysaccharides Induce Macrophage-Like Differentiation in Human Leukemia THP-1 Cells via Caspase and p53 Activation.

Hsu JW, Huang HC, Chen ST, Wong CH, Juan HF.

Evid Based Complement Alternat Med. 2011;2011:358717. doi: 10.1093/ecam/nep107. Epub 2011 Jan 4.

Functional expression of LZ-8, a fungal immunomodulatory protein from Ganoderma lucidium in Pichia pastoris.

Xue Q, Ding Y, Shang C, Jiang C, Zhao M.

J Gen Appl Microbiol. 2008 Dec;54(6):393-8.

Ganoderic acid Me inhibits tumor invasion through down-regulating matrix metalloproteinases 2/9 gene expression.

Chen NH, Liu JW, Zhong JJ.

J Pharmacol Sci. 2008 Oct;108(2):212-6.

Possible involvement of long chain fatty acids in the spores of Ganoderma lucidum (Reishi Houshi) to its anti-tumor activity.

Fukuzawa M, Yamaguchi R, Hide I, Chen Z, Hirai Y, Sugimoto A, Yasuhara T, Nakata Y.

Biol Pharm Bull. 2008 Oct;31(10):1933-7.

Ganoderma lucidum polysaccharides can induce human monocytic leukemia cells into dendritic cells with immuno-stimulatory function.

Chan WK, Cheung CC, Law HK, Lau YL, Chan GC.

J Hematol Oncol. 2008 Jul 21;1:9. doi: 10.1186/1756-8722-1-9.

Toxicity of a traditional Chinese medicine, Ganoderma lucidum, in children with cancer.

Gill SK, Rieder MJ.

Can J Clin Pharmacol. 2008 Summer;15(2):e275-85. Epub 2008 Jul 4.

Effects of the antlered form of Ganoderma lucidum on tumor growth and metastasis in cyclophosphamide-treated mice.

Nonaka Y, Ishibashi H, Nakai M, Shibata H, Kiso Y, Abe S.

Biosci Biotechnol Biochem. 2008 Jun;72(6):1399-408. Epub 2008 Jun 7.

Interaction of Ganoderma triterpenes with doxorubicin and proteomic characterization of the possible molecular targets of Ganoderma triterpenes.

Yue QX, Xie FB, Guan SH, Ma C, Yang M, Jiang BH, Liu X, Guo DA.

Cancer Sci. 2008 Jul;99(7):1461-70. doi: 10.1111/j.1349-7006.2008.00824.x. Epub 2008 Apr 16.

[Changes of serum interferon-gamma levels in mice bearing S-180 tumor and the interventional effect of immunomodulators].

Li L, Lei LS, Yu CL.

Nan Fang Yi Ke Da Xue Xue Bao. 2008 Jan;28(1):65-8. Chinese. 

Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network.

Yue QX, Cao ZW, Guan SH, Liu XH, Tao L, Wu WY, Li YX, Yang PY, Liu X, Guo DA.

Mol Cell Proteomics. 2008 May;7(5):949-61. doi: 10.1074/mcp.M700259-MCP200. Epub 2007 Dec 31.

[Effect of Ganoderma lucidum polysaccharides peptide on invasion of human lung carcinoma cells in vitro].

Cao QZ, Lin SQ, Wang SZ.

Beijing Da Xue Xue Bao. 2007 Dec 18;39(6):653-6. Chinese. 

Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-kappaB and AP-1.

Weng CJ, Chau CF, Hsieh YS, Yang SF, Yen GC.

Carcinogenesis. 2008 Jan;29(1):147-56. Epub 2007 Nov 16.

Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction.

Cheng KC, Huang HC, Chen JH, Hsu JW, Cheng HC, Ou CH, Yang WB, Chen ST, Wong CH, Juan HF.

BMC Genomics. 2007 Nov 9;8:411.

Antioxidant small phenolic ingredients in Inonotus obliquus (persoon) Pilat (Chaga).

Nakajima Y, Sato Y, Konishi T.

Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1222-6.

[Effect of Ganoderma lucidum polysaccharides on tumor cell nucleotide content and cell cycle in S180 ascitic tumor-bearing mice].

Li JJ, Lei LS, Yu CL, Zhu ZG, Zhang Q, Wu SG.

Nan Fang Yi Ke Da Xue Xue Bao. 2007 Jul;27(7):1003-5. Chinese. 

Response of human dendritic cells to different immunomodulatory polysaccharides derived from mushroom and barley.

Chan WK, Law HK, Lin ZB, Lau YL, Chan GC.

Int Immunol. 2007 Jul;19(7):891-9. Epub 2007 Jul 2.

Functional expression of FIP-gts, a fungal immunomodulatory protein from Ganoderma tsugae in Sf21 insect cells.

Jinn TR, Wu CM, Tu WC, Ko JL, Tzen JT.

Biosci Biotechnol Biochem. 2006 Nov;70(11):2627-34. Epub 2006 Nov 7.

Anti-tumor activities of the antlered form of Ganoderma lucidum in allogeneic and syngeneic tumor-bearing mice.

Nonaka Y, Shibata H, Nakai M, Kurihara H, Ishibashi H, Kiso Y, Tanaka T, Yamaguchi H, Abe S.

Biosci Biotechnol Biochem. 2006 Sep;70(9):2028-34. Epub 2006 Sep 7.

New anticancer agents: in vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants.

Kimura Y.

In Vivo. 2005 Jan-Feb;19(1):37-60. Review.

[Progress in research on Ganoderma lucidium spore].

Zhang W, Zeng YS.

Zhong Xi Yi Jie He Xue Bao. 2004 Nov;2(6):463-5. Review. Chinese. No abstract available. 

Medicinal mushroom extracts inhibit ras-induced cell transformation and the inhibitory effect requires the presence of normal cells.

Hsiao WL, Li YQ, Lee TL, Li N, You MM, Chang ST.

Carcinogenesis. 2004 Jul;25(7):1177-83.

Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide.

Cao QZ, Lin ZB.

Acta Pharmacol Sin. 2004 Jun;25(6):833-8.

Isoflavone aglycon produced by culture of soybean extracts with basidiomycetes and its anti-angiogenic activity.

Miura T, Yuan L, Sun B, Fujii H, Yoshida M, Wakame K, Kosuna K.

Biosci Biotechnol Biochem. 2002 Dec;66(12):2626-31.

Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancercell.

Hu H, Ahn NS, Yang X, Lee YS, Kang KS.

Int J Cancer. 2002 Nov 20;102(3):250-3.

Effects of polysaccharides (FI0-c) from mycelium of Ganoderma tsugae on proinflammatory cytokine production by THP-1 cells and human PBMC (II).

Gao XX, Wang BX, Fei XF, Zhang J, Gong YJ, Minami M, Nagata T, Ikejima T.

Acta Pharmacol Sin. 2000 Dec;21(12):1186-92.

Effects of polysaccharides (FI0-b) from mycelium of Ganoderma tsugae on proinflammatory cytokine production by THP-1 cells and human PBMC (I).

Gao XX, Fei XF, Wang BX, Zhang J, Gong YJ, Minami M, Nagata T, Ikejima T.

Acta Pharmacol Sin. 2000 Dec;21(12):1179-85.

Solution properties of antitumor sulfated derivative of alpha-(1-->3)-D-glucan from Ganodermalucidum.

Zhang L, Zhang M, Zhou Q, Chen J, Zeng F.

Biosci Biotechnol Biochem. 2000 Oct;64(10):2172-8.

Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells.

Cheung WM, Hui WS, Chu PW, Chiu SW, Ip NY.

FEBS Lett. 2000 Dec 15;486(3):291-6.

In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor).

Kim HS, Kacew S, Lee BM.

Carcinogenesis. 1999 Aug;20(8):1637-40.

The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes.

Wang SY, Hsu ML, Hsu HC, Tzeng CH, Lee SS, Shiao MS, Ho CK.

Int J Cancer. 1997 Mar 17;70(6):699-705.

Antitumor active protein-containing glycans from the Chinese mushroom songshan lingzhi, Ganoderma tsugae mycelium.

Zhang J, Wang G, Li H, Zhuang C, Mizuno T, Ito H, Mayuzumi H, Okamoto H, Li J.

Biosci Biotechnol Biochem. 1994 Jul;58(7):1202-5.

Antitumor active polysaccharides from the Chinese mushroom Songshan lingzhi, the fruiting body of Ganoderma tsugae.

Wang G, Zhang J, Mizuno T, Zhuang C, Ito H, Mayuzumi H, Okamoto H, Li J.

Biosci Biotechnol Biochem. 1993 Jun;57(6):894-900.

The Ethanolic Extract of Taiwanofungus camphoratus (Antrodia camphorata) Induces Cell Cycle Arrest and Enhances Cytotoxicity of Cisplatin and Doxorubicin on Human Hepatocellular Carcinoma Cells.

Lin LT, Tai CJ, Su CH, Chang FM, Choong CY, Wang CK, Tai CJ.

Biomed Res Int. 2015;2015:415269. doi: 10.1155/2015/415269. Epub 2015 Oct 18.

Intestinal Absorption of Ergostane and Lanostane Triterpenoids from Antrodia cinnamomea Using Caco-2 Cell Monolayer Model.

Wang Q, Qiao X, Qian Y, Li ZW, Tzeng YM, Zhou DM, Guo DA, Ye M.

Nat Prod Bioprospect. 2015 Oct;5(5):237-46. doi: 10.1007/s13659-015-0072-4. Epub 2015 Sep 28.

Antrodia camphorata Potentiates Neuroprotection against Cerebral Ischemia in Rats via Downregulation of iNOS/HO-1/Bax and Activated Caspase-3 and Inhibition of Hydroxyl Radical Formation.

Yang PS, Lin PY, Chang CC, Yu MC, Yen TL, Lan CC, Jayakumar T, Yang CH.

Evid Based Complement Alternat Med. 2015;2015:232789. doi: 10.1155/2015/232789. Epub 2015 Aug 25.

Apoptotic Effect of Extract from Medicinal Mushroom from Taiwan Taiwanofungus salmoneus (Higher Basidiomycetes) Mycelium Combined with or without Cisplatin on Hepatocellular Carcinoma Cells.

Chien RC, Hsieh YJ, Mau JL.

Int J Med Mushrooms. 2015;17(6):567-77.

Apoptosis of Hepatocellular Carcinoma Cells Induced by Nanoencapsulated Polysaccharides Extracted from Antrodia Camphorata.

Chang JS, Kuo HP, Chang KL, Kong ZL.

PLoS One. 2015 Sep 1;10(9):e0136782. doi: 10.1371/journal.pone.0136782. eCollection 2015.

Antrodia cinnamomea alleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice.

Huang TH, Chiu YH, Chan YL, Wang H, Li TL, Liu CY, Yang CT, Lee TY, You JS, Hsu KH, Wu CJ.

Oncotarget. 2015 Sep 22;6(28):25741-54. doi: 10.18632/oncotarget.4348.

4-Acetylantroquinonol B inhibits colorectal cancer tumorigenesis and suppresses cancer stem-like phenotype.

Chang TC, Yeh CT, Adebayo BO, Lin YC, Deng L, Rao YK, Huang CC, Lee WH, Wu AT, Hsiao M, Wu CH, Wang LS, Tzeng YM.

Toxicol Appl Pharmacol. 2015 Oct 15;288(2):258-68. doi: 10.1016/j.taap.2015.07.025. Epub 2015 Jul 30.

2,3,5-Trimethoxy-4-cresol, an anti-metastatic constituent from the solid-state cultured mycelium of Antrodia cinnamomea and its mechanism.

Lin CC, Chen CC, Kuo YH, Kuo JT, Senthil Kumar KJ, Wang SY.

J Nat Med. 2015 Oct;69(4):513-21. doi: 10.1007/s11418-015-0916-6. Epub 2015 May 8.

Metabolites identification and multi-component pharmacokinetics of ergostane and lanostane triterpenoids in the anticancer mushroom Antrodia cinnamomea.

Qiao X, Wang Q, Ji S, Huang Y, Liu KD, Zhang ZX, Bo T, Tzeng YM, Guo DA, Ye M.

J Pharm Biomed Anal. 2015 Jul 10;111:266-76. doi: 10.1016/j.jpba.2015.04.010. Epub 2015 Apr 10.

Antcin K, an Active Triterpenoid from the Fruiting Bodies of Basswood-Cultivated Antrodia cinnamomea, Inhibits Metastasis via Suppression of Integrin-Mediated Adhesion, Migration, and Invasion in Human Hepatoma Cells.

Huang YL, Chu YL, Ho CT, Chung JG, Lai CI, Su YC, Kuo YH, Sheen LY.

J Agric Food Chem. 2015 May 13;63(18):4561-9. doi: 10.1021/jf5059304. Epub 2015 May 5.

The adjuvant effects of high-molecule-weight polysaccharides purified from Antrodia cinnamomea on dendritic cell function and DNA vaccines.

Lin CC, Pan IH, Li YR, Pan YG, Lin MK, Lu YH, Wu HC, Chu CL.

PLoS One. 2015 Feb 27;10(2):e0116191. doi: 10.1371/journal.pone.0116191. eCollection 2015.

Anti-cancer agents derived from solid-state fermented Antrodia camphorata mycelium.

Yen IC, Yao CW, Kuo MT, Chao CL, Pai CY, Chang WL.

Ethanol extracts of Cinnamomum kanehirai Hayata leaves induce apoptosis in human hepatoma cell through caspase-3 cascade.

Liu YK, Chen KH, Leu YL, Way TD, Wang LW, Chen YJ, Liu YM.

Onco Targets Ther. 2014 Dec 31;8:99-109. doi: 10.2147/OTT.S68765. eCollection 2015.

Antrodin C inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via suppression of Smad2/3 and β-catenin signaling pathways.

Kumar KJ, Vani MG, Chueh PJ, Mau JL, Wang SY.

PLoS One. 2015 Feb 6;10(2):e0117111. doi: 10.1371/journal.pone.0117111. eCollection 2015.

Antroquinonol from Antrodia Camphorata suppresses breast tumor migration/invasion through inhibiting ERK-AP-1- and AKT-NF-κB-dependent MMP-9 and epithelial-mesenchymal transition expressions.

Lee WT, Lee TH, Cheng CH, Chen KC, Chen YC, Lin CW.

Food Chem Toxicol. 2015 Apr;78:33-41. doi: 10.1016/j.fct.2015.01.012. Epub 2015 Feb 2.

Efficacy of antioxidants as a Complementary and Alternative Medicine (CAM) in combination with the chemotherapeutic agent doxorubicin.

Sheu MT, Jhan HJ, Hsieh CM, Wang CJ, Ho HO.

Integr Cancer Ther. 2015 Mar;14(2):184-95. doi: 10.1177/1534735414564425. Epub 2014 Dec 25.

New and Cytotoxic Components from Antrodia camphorata.

Lee TH, Chen CC, Chen JJ, Liao HF, Chang HS, Sung PJ, Tseng MH, Wang SY, Ko HH, Kuo YH.

Molecules. 2014 Dec 19;19(12):21378-85. doi: 10.3390/molecules191221378.

Lyophilized particles and ethanolic extracts of Antrodia cinnamomea mycelia suppress the tumorigenicity of head and neck cancer cells in vivo.

Chang CW, Chen YS, Chen CC, Chen CC, Sheu SJ, Lin TW, Lee TC, Lo JF.

Biomedicine (Taipei). 2014;4:26. Epub 2014 Nov 22.

4-Acetylantroquinonol B suppresses tumor growth and metastasis of hepatoma cells via blockade of translation-dependent signaling pathway and VEGF production.

Chang CH, Huang TF, Lin KT, Hsu CC, Chang WL, Wang SW, Ko FN, Peng HC, Chung CH.

J Agric Food Chem. 2015 Jan 14;63(1):208-15.

Comparison of solid-state-cultured and wood-cultured Antrodia camphorata in anti-inflammatory effects using NF-κB/luciferase inducible transgenic mice.

Tung YT, Tsai TC, Kuo YH, Yen CC, Sun JY, Chang WH, Chen HL, Chen CM.

Phytomedicine. 2014 Oct 15;21(12):1708-16. doi: 10.1016/j.phymed.2014.08.011. Epub 2014 Sep 16.

Coenzyme Q0 from Antrodia cinnamomea in Submerged Cultures Induces Reactive Oxygen Species-Mediated Apoptosis in A549 Human Lung Cancer Cells.

Chung CH, Yeh SC, Chen CJ, Lee KT.

Evid Based Complement Alternat Med. 2014;2014:246748. doi: 10.1155/2014/246748. Epub 2014 Nov 6.

Genomic and transcriptomic analyses of the medicinal fungus Antrodia cinnamomea for its metabolite biosynthesis and sexual development.

Lu MY, Fan WL, Wang WF, Chen T, Tang YC, Chu FH, Chang TT, Wang SY, Li MY, Chen YH, Lin ZS, Yang KJ, Chen SM, Teng YC, Lin YL, Shaw JF, Wang TF, Li WH.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):E4743-52. doi: 10.1073/pnas.1417570111. Epub 2014 Oct 21.

Anticancer effects on human pancreatic cancer cells of triterpenoids, polysaccharides and 1,3-β-D-glucan derived from the fruiting body of Antrodia camphorata.

Lee CI, Wu CC, Hsieh SL, Lee CL, Chang YP, Chang CC, Wang YZ, Wang JJ.

Food Funct. 2014 Dec;5(12):3224-32. doi: 10.1039/c4fo00720d.

Antroquinonol blocks Ras and Rho signaling via the inhibition of protein isoprenyltransferase activity in cancer cells.

Ho CL, Wang JL, Lee CC, Cheng HY, Wen WC, Cheng HH, Chen MC.

Biomed Pharmacother. 2014 Oct;68(8):1007-14. doi: 10.1016/j.biopha.2014.09.008. Epub 2014 Sep 26.

CARI III inhibits tumor growth in a melanoma-bearing mouse model through induction of G0/G1 cell cycle arrest.

Park HJ.

Molecules. 2014 Sep 12;19(9):14383-95. doi: 10.3390/molecules190914383.

Effectiveness of a novel herbal agent MB-6 as a potential adjunct to 5-fluoracil-based chemotherapy in colorectal cancer.

Chen WT, Yang TS, Chen HC, Chen HH, Chiang HC, Lin TC, Yeh CH, Ke TW, Chen JS, Hsiao KH, Kuo ML.

Nutr Res. 2014 Jul;34(7):585-94. doi: 10.1016/j.nutres.2014.06.010. Epub 2014 Jun 24.

Extract of Antrodia camphorata exerts neuroprotection against embolic stroke in rats without causing the risk of hemorrhagic incidence.

Lee YM, Chang CY, Yen TL, Geraldine P, Lan CC, Sheu JR, Lee JJ.

ScientificWorldJournal. 2014;2014:686109. doi: 10.1155/2014/686109. Epub 2014 Jul 21.

Antrodia camphorata induces G(1) cell-cycle arrest in human premyelocytic leukemia (HL-60) cells and suppresses tumor growth in athymic nude mice.

Yang HL, Kumar KJ, Kuo YT, Chang HC, Liao JW, Hsu LS, Hseu YC.

Food Funct. 2014 Sep;5(9):2278-88. doi: 10.1039/c4fo00423j.

The medicinal fungus Antrodia cinnamomea suppresses inflammation by inhibiting the NLRP3 inflammasome.

Huang TT, Wu SP, Chong KY, Ojcius DM, Ko YF, Wu YH, Wu CY, Lu CC, Martel J, Young JD, Lai HC.

J Ethnopharmacol. 2014 Aug 8;155(1):154-64. doi: 10.1016/j.jep.2014.04.053. Epub 2014 May 20.

Antroquinonol D, isolated from Antrodia camphorata, with DNA demethylation and anticancer potential.

Wang SC, Lee TH, Hsu CH, Chang YJ, Chang MS, Wang YC, Ho YS, Wen WC, Lin RK.

J Agric Food Chem. 2014 Jun 18;62(24):5625-35. doi: 10.1021/jf4056924. Epub 2014 Jun 6.

Radioprotective effects of Antrodia cinnamomea are enhanced on immune cells and inhibited on cancer cells.

Cheng PC, Huang CC, Chiang PF, Lin CN, Li LL, Lee TW, Lin B, Chen IC, Chang KW, Fan CK, Luo TY.

Int J Radiat Biol. 2014 Oct;90(10):841-52. doi: 10.3109/09553002.2014.911989. Epub 2014 Aug 11.

The anti-tumor activity of Antrodia salmonea in human promyelocytic leukemia (HL-60) cells is mediated via the induction of G₁ cell-cycle arrest and apoptosis in vitro or in vivo.

Hseu YC, Lee CC, Chen YC, Kumar KJ, Chen CS, Huang YC, Hsu LS, Huang HC, Yang HL.

J Ethnopharmacol. 2014 Apr 28;153(2):499-510. doi: 10.1016/j.jep.2014.03.012. Epub 2014 Mar 14.

Antcamphins A-L, ergostanoids from Antrodia camphorata.

Huang Y, Lin X, Qiao X, Ji S, Liu K, Yeh CT, Tzeng YM, Guo D, Ye M.

J Nat Prod. 2014 Jan 24;77(1):118-24. doi: 10.1021/np400741s. Epub 2014 Jan 3.

Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells.

Chen YJ, Thang MW, Chan YT, Huang YF, Ma N, Yu AL, Wu CY, Hu ML, Chiu KP.

PLoS One. 2013 Dec 17;8(12):e82751. doi: 10.1371/journal.pone.0082751. eCollection 2013.

Cytotoxic effect and induction of apoptosis in human cervical cancer cells by Antrodia camphorata.

Yang PY, Hu DN, Liu FS.

Am J Chin Med. 2013;41(5):1169-80. doi: 10.1142/S0192415X13500791.

Mycotherapy of cancer: an update on cytotoxic and antitumor activities of mushrooms, bioactive principles and molecular mechanisms of their action.

Popović V, Živković J, Davidović S, Stevanović M, Stojković D.

Curr Top Med Chem. 2013;13(21):2791-806. Review.

Antrodia camphorata grown on germinated brown rice inhibits HT-29 human colon carcinoma proliferation through inducing G0/G1 phase arrest and apoptosis by targeting the β-catenin signaling.

Park DK, Lim YH, Park HJ.

J Med Food. 2013 Aug;16(8):681-91. doi: 10.1089/jmf.2012.2605.

Enhancement of 4-acetylantroquinonol B production by supplementation of its precursor during submerged fermentation of Antrodia cinnamomea.

Chiang CC, Huang TN, Lin YW, Chen KH, Chiang BH.

J Agric Food Chem. 2013 Sep 25;61(38):9160-5. doi: 10.1021/jf402187q. Epub 2013 Sep 10.

A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.

Yeh CT, Huang WC, Rao YK, Ye M, Lee WH, Wang LS, Tzeng DT, Wu CH, Shieh YS, Huang CY, Chen YJ, Hsiao M, Wu AT, Yang Z, Tzeng YM.

Carcinogenesis. 2013 Dec;34(12):2918-28. doi: 10.1093/carcin/bgt255. Epub 2013 Jul 23.

Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death.

Chang CW, Chen CC, Wu MJ, Chen YS, Chen CC, Sheu SJ, Lin TW, Chou SH, Lin SC, Liu CJ, Lee TC, Huang CY, Lo JF.

Evid Based Complement Alternat Med. 2013;2013:946451. doi: 10.1155/2013/946451. Epub 2013 Jun 12.

Isolation and synthesis of a bioactive benzenoid derivative from the fruiting bodies of Antrodiacamphorata.

Chen PY, Wu JD, Tang KY, Yu CC, Kuo YH, Zhong WB, Lee CK.

Molecules. 2013 Jun 28;18(7):7600-8. doi: 10.3390/molecules18077600.

The anti-cancer activity of Antrodia camphorata against human ovarian carcinoma (SKOV-3) cells via modulation of HER-2/neu signaling pathway.

Yang HL, Lin KY, Juan YC, Kumar KJ, Way TD, Shen PC, Chen SC, Hseu YC.

J Ethnopharmacol. 2013 Jun 21;148(1):254-65. doi: 10.1016/j.jep.2013.04.023. Epub 2013 Apr 22.

Elucidating the inhibitory mechanisms of the ethanolic extract of the fruiting body of the mushroom Antrodia cinnamomea on the proliferation and migration of murine leukemia WEHI-3 cells and their tumorigenicity in a BALB/c allograft tumor model.

Liu FC, Lai MT, Chen YY, Lin WH, Chang SJ, Sheu MJ, Wu CH.

Phytomedicine. 2013 Jul 15;20(10):874-82. doi: 10.1016/j.phymed.2013.03.008. Epub 2013 Apr 20.

Medicinal Fungus Antrodia cinnamomea Inhibits Growth and Cancer Stem Cell Characteristics of Hepatocellular Carcinoma.

Liu YM, Liu YK, Lan KL, Lee YW, Tsai TH, Chen YJ.

Evid Based Complement Alternat Med. 2013;2013:569737. doi: 10.1155/2013/569737. Epub 2013 Mar 6.

Methyl Antcinate A suppresses the population of cancer stem-like cells in MCF7 human breast cancercell line.

Peng CY, Fong PC, Yu CC, Tsai WC, Tzeng YM, Chang WW.

Molecules. 2013 Feb 26;18(3):2539-48. doi: 10.3390/molecules18032539.

Inhibition of Helicobacter pylori CagA-Induced Pathogenesis by Methylantcinate B from Antrodiacamphorata.

Lin CJ, Rao YK, Hung CL, Feng CL, Lane HY, Tzeng DT, Hsu PN, Lai CH, Tzeng YM.

Evid Based Complement Alternat Med. 2013;2013:682418. doi: 10.1155/2013/682418. Epub 2013 Jan 8.

The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate.

Wei PL, Tu SH, Lien HM, Chen LC, Chen CS, Wu CH, Huang CS, Chang HW, Chang CH, Tseng H, Ho YS.

J Cancer Res Ther. 2012 Oct-Dec;8(4):532-6. doi: 10.4103/0973-1482.106529.

Eburicoic Acid, an Active Triterpenoid from the Fruiting Bodies of Basswood Cultivated Antrodiacinnamomea, Induces ER Stress-Mediated Autophagy in Human Hepatoma Cells.

Su YC, Liu CT, Chu YL, Raghu R, Kuo YH, Sheen LY.

J Tradit Complement Med. 2012 Oct;2(4):312-22.

Protective effects of Antrodia cinnamomea against liver injury.

Liu YW, Lu KH, Ho CT, Sheen LY.

J Tradit Complement Med. 2012 Oct;2(4):284-94. Review.

Characterization of fungal sulfated polysaccharides and their synergistic anticancer effects with doxorubicin.

Cheng JJ, Chang CC, Chao CH, Lu MK.

Carbohydr Polym. 2012 Sep 1;90(1):134-9. doi: 10.1016/j.carbpol.2012.05.005. Epub 2012 May 8.

Triterpenoid-Rich Extract from Antrodia camphorata Improves Physical Fatigue and Exercise Performance in Mice.

Huang CC, Hsu MC, Huang WC, Yang HR, Hou CC.

Evid Based Complement Alternat Med. 2012;2012:364741. doi: 10.1155/2012/364741. Epub 2012 Jul 5.

Taiwanofungus camphoratus (Syn Antrodia camphorata) extract and amphotericin B exert adjuvant effects via mitochondrial apoptotic pathway.

Chen LY, Sheu MT, Liao CK, Tsai FC, Kao WY, Su CH.

Integr Cancer Ther. 2013 Mar;12(2):153-64. doi: 10.1177/1534735412442379. Epub 2012 Jul 12.

Anticancer effects of eleven triterpenoids derived from Antrodia camphorata.

Lee YP, Tsai WC, Ko CJ, Rao YK, Yang CR, Chen DR, Yang MH, Yang CC, Tzeng YM.

Anticancer Res. 2012 Jul;32(7):2727-34.

Inhibition of Cell Growth and Induction of Apoptosis by Antrodia camphorata in HER-2/neu-Overexpressing Breast Cancer Cells through the Induction of ROS, Depletion of HER-2/neu, and Disruption of the PI3K/Akt Signaling Pathway.

Lee CC, Yang HL, Way TD, Kumar KJ, Juan YC, Cho HJ, Lin KY, Hsu LS, Chen SC, Hseu YC.

Evid Based Complement Alternat Med. 2012;2012:702857. doi: 10.1155/2012/702857. Epub 2012 Jun 3.

Recent developments in mushrooms as anti-cancer therapeutics: a review.

Patel S, Goyal A.

3 Biotech. 2012 Mar;2(1):1-15. Epub 2011 Nov 25.

Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models.

Du YC, Chang FR, Wu TY, Hsu YM, El-Shazly M, Chen CF, Sung PJ, Lin YY, Lin YH, Wu YC, Lu MC.

Phytomedicine. 2012 Jun 15;19(8-9):788-96. doi: 10.1016/j.phymed.2012.03.014. Epub 2012 Apr 18.

Ethanol extracts of fruiting bodies of Antrodia cinnamomea exhibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways.

Chen YY, Chou PY, Chien YC, Wu CH, Wu TS, Sheu MJ.

Phytomedicine. 2012 Jun 15;19(8-9):768-78. doi: 10.1016/j.phymed.2012.02.016. Epub 2012 Mar 29. Erratum in: Phytomedicine. 2012 Dec 15;20(1):1-2. 

Ethanol extracts of fruiting bodies of Antrodia cinnamomea suppress CL1-5 human lung adenocarcinoma cells migration by inhibiting matrix metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt signaling pathways.

Chen YY, Liu FC, Chou PY, Chien YC, Chang WS, Huang GJ, Wu CH, Sheu MJ.

Evid Based Complement Alternat Med. 2012;2012:378415. doi: 10.1155/2012/378415. Epub 2012 Feb 21. Erratum in: Evid Based Complement Alternat Med. 2013;2013:423987. 

In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway.

Tu SH, Wu CH, Chen LC, Huang CS, Chang HW, Chang CH, Lien HM, Ho YS.

J Agric Food Chem. 2012 Apr 11;60(14):3612-8. doi: 10.1021/jf300221g. Epub 2012 Mar 29.

Inhibition of cell survival, cell cycle progression, tumor growth and cyclooxygenase-2 activity in MDA-MB-231 breast cancer cells by camphorataimide B.

Lin WL, Lee YJ, Wang SM, Huang PY, Tseng TH.

Eur J Pharmacol. 2012 Apr 5;680(1-3):8-15. doi: 10.1016/j.ejphar.2012.01.032. Epub 2012 Feb 10.

Chemical profiling of the cytotoxic triterpenoid-concentrating fraction and characterization of ergostane stereo-isomer ingredients from Antrodia camphorata.

Du YC, Wu TY, Chang FR, Lin WY, Hsu YM, Cheng FT, Lu CY, Yen MH, Tsui YT, Chen HL, Hou MF, Lu MC, Wu YC.

J Pharm Biomed Anal. 2012 Jan 25;58:182-92. doi: 10.1016/j.jpba.2011.09.007. Epub 2011 Sep 16.

Antcin B and its ester derivative from Antrodia camphorata induce apoptosis in hepatocellular carcinoma cells involves enhancing oxidative stress coincident with activation of intrinsic and extrinsic apoptotic pathway.

Hsieh YC, Rao YK, Whang-Peng J, Huang CY, Shyue SK, Hsu SL, Tzeng YM.

J Agric Food Chem. 2011 Oct 26;59(20):10943-54. doi: 10.1021/jf202771d. Epub 2011 Oct 5.

Pretreatment with an ethanolic extract of Taiwanofungus camphoratus (Antrodia camphorata) enhances the cytotoxic effects of amphotericin B.

Chen LY, Sheu MT, Liu DZ, Liao CK, Ho HO, Kao WY, Ho YS, Lee WS, Su CH.

J Agric Food Chem. 2011 Oct 26;59(20):11255-63. doi: 10.1021/jf2024215. Epub 2011 Sep 25.

Antrodia camphorata induces apoptosis and enhances the cytotoxic effect of paclitaxel in human ovarian cancer cells.

Liu FS, Yang PY, Hu DN, Huang YW, Chen MJ.

Int J Gynecol Cancer. 2011 Oct;21(7):1172-9. doi: 10.1097/IGC.0b013e31821f742c.

Antroquinonol, a natural ubiquinone derivative, induces a cross talk between apoptosis, autophagy and senescence in human pancreatic carcinoma cells.

Yu CC, Chiang PC, Lu PH, Kuo MT, Wen WC, Chen P, Guh JH.

J Nutr Biochem. 2012 Aug;23(8):900-7. doi: 10.1016/j.jnutbio.2011.04.015. Epub 2011 Aug 12.

A Preclinical Evaluation of Antrodia camphorata Alcohol Extracts in the Treatment of Non-Small Cell Lung Cancer Using Non-Invasive Molecular Imaging.

Chiou JF, Wu AT, Wang WT, Kuo TH, Gelovani JG, Lin IH, Wu CH, Chiu WT, Deng WP.

Evid Based Complement Alternat Med. 2011;2011:914561. doi: 10.1093/ecam/nep228. Epub 2011 Mar 13.

Study of the Anti-Proliferative Activity of 5-Substituted 4,7-Dimethoxy-1,3-Benzodioxole Derivatives of SY-1 from Antrodia camphorata on Human COLO 205 Colon Cancer Cells.

Lien HM, Kuo PT, Huang CL, Kao JY, Lin H, Yang DY, Lai YY.

Evid Based Complement Alternat Med. 2011;2011:450529. doi: 10.1093/ecam/nep230. Epub 2011 May 3. Erratum in: Evid Based Complement Alternat Med. 2012;2012:148127. 

4-acetylantroquinonol B isolated from Antrodia cinnamomea arrests proliferation of human hepatocellular carcinoma HepG2 cell by affecting p53, p21 and p27 levels.

Lin YW, Chiang BH.

J Agric Food Chem. 2011 Aug 24;59(16):8625-31. doi: 10.1021/jf2011326. Epub 2011 Jul 26.

Macrophage mediated anti-proliferation effects of Anthodia camphorata non-polysaccharide based extracts on human hepatoma cells.

Chang CY, Cheng TJ, Chang FR, Wang HY, Kan WC, Li SL, Huang LH, Chen YC, Tsai WC, Huang CH, Cheng CH, Lee GY, Shyue SW, Chen YP, Lin KC, Chuu JJ.

Biosci Biotechnol Biochem. 2011;75(4):624-32. Epub 2011 Apr 22.

Antroquinonol inhibits NSCLC proliferation by altering PI3K/mTOR proteins and miRNA expression profiles.

Kumar VB, Yuan TC, Liou JW, Yang CJ, Sung PJ, Weng CF.

Mutat Res. 2011 Feb 10;707(1-2):42-52. doi: 10.1016/j.mrfmmm.2010.12.009. Epub 2010 Dec 24.

Identification of antrocin from Antrodia camphorata as a selective and novel class of small molecule inhibitor of Akt/mTOR signaling in metastatic breast cancer MDA-MB-231 cells.

Rao YK, Wu AT, Geethangili M, Huang MT, Chao WJ, Wu CH, Deng WP, Yeh CT, Tzeng YM.

Chem Res Toxicol. 2011 Feb 18;24(2):238-45. doi: 10.1021/tx100318m. Epub 2010 Dec 15.

Anti-metastatic activities of Antrodia camphorata against human breast cancer cells mediated through suppression of the MAPK signaling pathway.

Yang HL, Kuo YH, Tsai CT, Huang YT, Chen SC, Chang HW, Lin E, Lin WH, Hseu YC.

Food Chem Toxicol. 2011 Jan;49(1):290-8. doi: 10.1016/j.fct.2010.10.031. Epub 2010 Nov 4.

Methylantcinate A induces tumor specific growth inhibition in oral cancer cells via Bax-mediated mitochondrial apoptotic pathway.

Tsai WC, Rao YK, Lin SS, Chou MY, Shen YT, Wu CH, Geethangili M, Yang CC, Tzeng YM.

Bioorg Med Chem Lett. 2010 Oct 15;20(20):6145-8. doi: 10.1016/j.bmcl.2010.08.006. Epub 2010 Aug 6.

Dietary effect of Antrodia Camphorate extracts on immune responses in WEHI-3 leukemia BALB/c mice.

Lin SY, Sheen LY, Chiang BH, Yang JS, Pan JH, Chang YH, Hsu YM, Chiang JH, Lu CC, Wu CL, Chung JG.

Nutr Cancer. 2010;62(5):593-600. doi: 10.1080/01635580903532341.

The 4-acetylantroquinonol B isolated from mycelium of Antrodia cinnamomea inhibits proliferation of hepatoma cells.

Lin YW, Pan JH, Liu RH, Kuo YH, Sheen LY, Chiang BH.

J Sci Food Agric. 2010 Aug 15;90(10):1739-44. doi: 10.1002/jsfa.4010.

Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway.

Hsieh YC, Rao YK, Wu CC, Huang CY, Geethangili M, Hsu SL, Tzeng YM.

Chem Res Toxicol. 2010 Jul 19;23(7):1256-67. doi: 10.1021/tx100116a.

Promoting effect of Antrodia camphorata as an immunomodulating adjuvant on the antitumor efficacy of HER-2/neu DNA vaccine.

Huang CH, Chang CC, Lin CM, Wang ST, Wu MT, Li EI, Chang HC, Lin CC.

Cancer Immunol Immunother. 2010 Aug;59(8):1259-72. doi: 10.1007/s00262-010-0852-y.

Apoptotic effects of a high performance liquid chromatography (HPLC) fraction of Antrodiacamphorata mycelia are mediated by down-regulation of the expressions of four tumor-related genes in human non-small cell lung carcinoma A549 cell.

Chan YY, Chang CS, Chien LH, Wu TF.

J Ethnopharmacol. 2010 Feb 17;127(3):652-61. doi: 10.1016/j.jep.2009.12.008. Epub 2009 Dec 6.

Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma.

Liu KJ, Leu SJ, Su CH, Chiang BL, Chen YL, Lee YL.

Immunology. 2010 Mar;129(3):351-62. doi: 10.1111/j.1365-2567.2009.03175.x. Epub 2009 Nov 11.

Dehydroeburicoic acid induces calcium- and calpain-dependent necrosis in human U87MG glioblastomas.

Deng JY, Chen SJ, Jow GM, Hsueh CW, Jeng CJ.

Chem Res Toxicol. 2009 Nov;22(11):1817-26. doi: 10.1021/tx9002275.

Effects of Antrodia camphorata extracts on the viability, apoptosis, [Ca2+]i, and MAPKs phosphorylation of OC2 human oral cancer cells.

Huang CC, Cheng HH, Wang JL, Cheng JS, Chai KL, Fang YC, Kuo CC, Chu ST, Ho CM, Lin KL, Tsai JY, Jan CR.

Chin J Physiol. 2009 Jun 30;52(3):128-35.

Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: a crucial role of AMPK and mTOR pathways.

Chiang PC, Lin SC, Pan SL, Kuo CH, Tsai IL, Kuo MT, Wen WC, Chen P, Guh JH.

Biochem Pharmacol. 2010 Jan 15;79(2):162-71. doi: 10.1016/j.bcp.2009.08.022. Epub 2009 Aug 31.

Review of Pharmacological Effects of Antrodia camphorata and Its Bioactive Compounds.

Geethangili M, Tzeng YM.

Evid Based Complement Alternat Med. 2011;2011:212641. doi: 10.1093/ecam/nep108. Epub 2011 Jan 3.

The augmented anti-tumor effects of Antrodia camphorata co-fermented with Chinese medicinal herb in human hepatoma cells.

Li SL, Huang ZN, Hsieh HH, Yu WC, Tzeng WY, Lee GY, Chen YP, Chang CY, Chuu JJ.

Am J Chin Med. 2009;37(4):771-83.

Anti-angiogenic effects and mechanisms of polysaccharides from Antrodia cinnamomea with different molecular weights.

Yang CM, Zhou YJ, Wang RJ, Hu ML.

J Ethnopharmacol. 2009 Jun 25;123(3):407-12. doi: 10.1016/j.jep.2009.03.034. Epub 2009 Mar 31.

Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells.

Yeh CT, Rao YK, Yao CJ, Yeh CF, Li CH, Chuang SE, Luong JH, Lai GM, Tzeng YM.

Cancer Lett. 2009 Nov 18;285(1):73-9. doi: 10.1016/j.canlet.2009.05.002. Epub 2009 May 23.

A novel inhibitory effect of Antrodia camphorata extract on vascular smooth muscle cell migration and neointima formation in mice.

Li YH, Chung HC, Liu SL, Chao TH, Chen JC.

Int Heart J. 2009 Mar;50(2):207-20.

Compound MMH01 possesses toxicity against human leukemia and pancreatic cancer cells.

Chen YJ, Chou CJ, Chang TT.

Toxicol In Vitro. 2009 Apr;23(3):418-24. doi: 10.1016/j.tiv.2009.01.011. Epub 2009 Jan 22.

Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-Methyl-l,3-Benzodioxole Isolated from the Fruiting Body of Antrodia camphorate.

Lien HM, Lin HW, Wang YJ, Chen LC, Yang DY, Lai YY, Ho YS.

Evid Based Complement Alternat Med. 2011;2011:984027. doi: 10.1093/ecam/nep020. Epub 2011 Jun 8.

Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases.

Ao ZH, Xu ZH, Lu ZM, Xu HY, Zhang XM, Dou WF.

J Ethnopharmacol. 2009 Jan 21;121(2):194-212. doi: 10.1016/j.jep.2008.10.039. Epub 2008 Nov 17. Review.

Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease.

Phuong do T, Ma CM, Hattori M, Jin JS.

Phytother Res. 2009 Apr;23(4):582-4. doi: 10.1002/ptr.2657.

Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A.

Lu MC, Du YC, Chuu JJ, Hwang SL, Hsieh PC, Hung CS, Chang FR, Wu YC.

Arch Toxicol. 2009 Feb;83(2):121-9. doi: 10.1007/s00204-008-0337-3. Epub 2008 Aug 16.

Effects of antrodia camphorata on viability, apoptosis, and [Ca2+]i in PC3 human prostate cancercells.

Ho CM, Huang CC, Huang CJ, Cheng JS, Chen IS, Tsai JY, Jiann BP, Tseng PL, Kuo SJ, Jan CR.

Chin J Physiol. 2008 Apr 30;51(2):78-84. Erratum in: Chin J Physiol. 2008 Jun 30;51(3):196. 

The adjuvant effects of Antrodia Camphorata extracts combined with anti-tumor agents on multidrug resistant human hepatoma cells.

Chang CY, Huang ZN, Yu HH, Chang LH, Li SL, Chen YP, Lee KY, Chuu JJ.

J Ethnopharmacol. 2008 Aug 13;118(3):387-95. doi: 10.1016/j.jep.2008.05.001. Epub 2008 May 7.

Antrodia camphorata inhibits proliferation of human breast cancer cells in vitro and in vivo.

Hseu YC, Chen SC, Chen HC, Liao JW, Yang HL.

Food Chem Toxicol. 2008 Aug;46(8):2680-8. doi: 10.1016/j.fct.2008.04.036. Epub 2008 May 4.

Polysaccharides from Antrodia camphorata mycelia extracts possess immunomodulatory activity and inhibits infection of Schistosoma mansoni.

Chen YJ, Cheng PC, Lin CN, Liao HF, Chen YY, Chen CC, Lee KM.

Int Immunopharmacol. 2008 Mar;8(3):458-67. doi: 10.1016/j.intimp.2007.11.008. Epub 2007 Dec 28.

In vivo immunomodulatory effects of Antrodia camphorata polysaccharides in a T1/T2 doubly transgenic mouse model for inhibiting infection of Schistosoma mansoni.

Cheng PC, Hsu CY, Chen CC, Lee KM.

Toxicol Appl Pharmacol. 2008 Mar 1;227(2):291-8. Epub 2007 Nov 7.

Evaluation of the anti-inflammatory and anti-proliferation tumoral cells activities of Antrodiacamphorata, Cordyceps sinensis, and Cinnamomum osmophloeum bark extracts.

Rao YK, Fang SH, Tzeng YM.

J Ethnopharmacol. 2007 Oct 8;114(1):78-85. Epub 2007 Aug 2.

Unique formosan mushroom Antrodia camphorata differentially inhibits androgen-responsive LNCaP and -independent PC-3 prostate cancer cells.

Chen KC, Peng CC, Peng RY, Su CH, Chiang HS, Yan JH, Hsieh-Li HM.

Nutr Cancer. 2007;57(1):111-21.

Inhibition of cyclooxygenase-2 and induction of apoptosis in estrogen-nonresponsive breast cancercells by Antrodia camphorata.

Hseu YC, Chen SC, Tsai PC, Chen CS, Lu FJ, Chang NW, Yang HL.

Food Chem Toxicol. 2007 Jul;45(7):1107-15. Epub 2006 Dec 27.

Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancercell line PLC/PRF/5 through inhibition of nuclear factor kappaB pathway.

Hsu YL, Kuo PL, Cho CY, Ni WC, Tzeng TF, Ng LT, Kuo YH, Lin CC.

Food Chem Toxicol. 2007 Jul;45(7):1249-57. Epub 2007 Jan 17.

Antrodia camphorata extract induces replicative senescence in superficial TCC, and inhibits the absolute migration capability in invasive bladder carcinoma cells.

Peng CC, Chen KC, Peng RY, Chyau CC, Su CH, Hsieh-Li HM.

J Ethnopharmacol. 2007 Jan 3;109(1):93-103. Epub 2006 Jul 11.

Apoptotic effects of Antrodia cinnamomea fruiting bodies extract are mediated through calcium and calpain-dependent pathways in Hep 3B cells.

Kuo PL, Hsu YL, Cho CY, Ng LT, Kuo YH, Lin CC.

Food Chem Toxicol. 2006 Aug;44(8):1316-26. Epub 2006 Feb 28.

Human urinary bladder cancer T24 cells are susceptible to the Antrodia camphorata extracts.

Peng CC, Chen KC, Peng RY, Su CH, Hsieh-Li HM.

Cancer Lett. 2006 Nov 8;243(1):109-19. Epub 2006 Feb 7.

Proteomic analysis of the effect of Antrodia camphorata extract on human lung cancer A549 cell.

Wu H, Pan CL, Yao YC, Chang SS, Li SL, Wu TF.

Proteomics. 2006 Feb;6(3):826-35.

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Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by Antrodia camphorata.

Yang HL, Chen CS, Chang WH, Lu FJ, Lai YC, Chen CC, Hseu TH, Kuo CT, Hseu YC.

Cancer Lett. 2006 Jan 18;231(2):215-27.

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